Transcribed genes |
Gene | Score | GO annotation |
IER3 | 26 |
BP MF CC |
biological_process | - anatomical structure morphogenesis
- anti-apoptosis
- apoptosis
|
| cellular_component | - integral to membrane
- membrane
|
| | |
BTG1 | 26 |
BP MF CC |
biological_process | - cell migration
- negative regulation of cell growth
- negative regulation of cell proliferation
- positive regulation of angiogenesis
more... - positive regulation of endothelial cell differentiation
- positive regulation of myoblast differentiation
- regulation of apoptosis
- regulation of transcription, DNA-dependent
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|
| | molecular_function | - enzyme binding
- kinase binding
- protein binding
- transcription cofactor activity
more...
|
| |
OGT | 24 |
BP MF CC |
biological_process | - cellular response to retinoic acid
- positive regulation of catalytic activity
- positive regulation of granulocyte differentiation
- positive regulation of histone H3-K4 methylation
more... - positive regulation of proteolysis
- protein O-linked glycosylation
- protein homotrimerization
- response to nutrient
- signal transduction
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|
| cellular_component | - MLL5-L complex
- cytoplasm
- cytosol
- nucleus
more...
|
| molecular_function | - acetylglucosaminyltransferase activity
- enzyme activator activity
- monosaccharide binding
- peptide binding
more... - protein N-acetylglucosaminyltransferase activity
- protein binding
- transferase activity, transferring glycosyl groups
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|
| |
IDI1 | 24 |
BP MF CC |
biological_process | - cholesterol biosynthetic process
- isoprenoid biosynthetic process
- response to stilbenoid
|
| cellular_component | - cytosol
- mitochondrion
- peroxisome
|
| molecular_function | - hydrolase activity
- isomerase activity
- isopentenyl-diphosphate delta-isomerase activity
- metal ion binding
more...
|
| |
USP9X | 22 |
BP MF CC |
biological_process | - BMP signaling pathway
- cell cycle
- cell division
- chromosome segregation
more... - female gamete generation
- mitosis
- protein deubiquitination
- transforming growth factor beta receptor signaling pathway
- ubiquitin-dependent protein catabolic process
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|
| | | |
GOLGA2 | 22 |
BP MF CC |
| cellular_component | - Golgi apparatus
- Golgi cisterna membrane
- membrane
|
| | |
ATF3 | 22 |
BP MF CC |
biological_process | - gluconeogenesis
- negative regulation of transcription, DNA-dependent
- positive regulation of cell proliferation
- regulation of transcription, DNA-dependent
more... - transcription, DNA-dependent
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|
| cellular_component | - nucleolus
- nucleoplasm
- nucleus
|
| | |
RAB5A | 22 |
BP MF CC |
biological_process | - GTP catabolic process
- blood coagulation
- cell differentiation
- endocytosis
more... - nervous system development
- positive regulation of exocytosis
- protein transport
- receptor internalization involved in canonical Wnt receptor signaling pathway
- regulation of filopodium assembly
- small GTPase mediated signal transduction
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|
| | | |
LAMP3 | 22 |
BP MF CC |
| cellular_component | - integral to membrane
- lysosomal membrane
- membrane
|
| | |
TNFRSF10B | 22 |
BP MF CC |
biological_process | - activation of NF-kappaB-inducing kinase activity
- activation of caspase activity
- activation of pro-apoptotic gene products
- apoptosis
more... - cell surface receptor linked signaling pathway
- cellular response to mechanical stimulus
- induction of apoptosis by extracellular signals
- induction of apoptosis via death domain receptors
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- regulation of apoptosis
- signal transduction
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|
| cellular_component | - integral to membrane
- plasma membrane
|
| molecular_function | - TRAIL binding
- caspase activator activity
- protein binding
- receptor activity
more...
|
| |
NFIL3 | 22 |
BP MF CC |
biological_process | - circadian rhythm
- immune response
- regulation of transcription, DNA-dependent
- transcription from RNA polymerase II promoter
more...
|
| | | |
HMGCR | 22 |
BP MF CC |
biological_process | - aging
- cholesterol biosynthetic process
- coenzyme A metabolic process
- embryo development
more... - germ cell migration
- gonad development
- isoprenoid biosynthetic process
- negative regulation of MAP kinase activity
- oxidation-reduction process
- positive regulation of skeletal muscle tissue development
- response to nutrient
- visual learning
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|
| | | |
HBEGF | 22 |
BP MF CC |
biological_process | - epidermal growth factor receptor signaling pathway
- muscle organ development
- negative regulation of elastin biosynthetic process
- positive regulation of cell growth
more... - positive regulation of cell migration
- positive regulation of keratinocyte migration
- positive regulation of protein kinase B signaling cascade
- positive regulation of smooth muscle cell proliferation
- positive regulation of wound healing
- regulation of heart contraction
- signal transduction
- wound healing, spreading of epidermal cells
less...
|
| cellular_component | - cell surface
- extracellular region
- extracellular space
- integral to plasma membrane
more... - plasma membrane
less...
|
| molecular_function | - epidermal growth factor receptor binding
- eukaryotic cell surface binding
- growth factor activity
- heparin binding
more... - receptor activity
less...
|
| |
TAX1BP1 | 22 |
BP MF CC |
| | molecular_function | - kinase binding
- protein binding
- zinc ion binding
|
| |
SARS | 22 |
BP MF CC |
biological_process | - gene expression
- seryl-tRNA aminoacylation
- tRNA aminoacylation for protein translation
- tRNA processing
more... - translation
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|
| cellular_component | - cytoplasm
- cytosol
- mitochondrion
|
| | |
LPIN1 | 22 |
BP MF CC |
biological_process | - actin cytoskeleton reorganization
- cellular lipid metabolic process
- cellular response to insulin stimulus
- fatty acid catabolic process
more... - lipid metabolic process
- mitochondrial fission
- negative regulation of transcription from RNA polymerase II promoter
- organ regeneration
- positive regulation of histone deacetylation
- positive regulation of transcription from RNA polymerase II promoter
- regulation of fat cell differentiation
- regulation of transcription, DNA-dependent
- ruffle organization
- triglyceride biosynthetic process
- triglyceride mobilization
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|
| | molecular_function | - RNA polymerase II transcription factor binding
- histone deacetylase binding
- hydrolase activity
- molecular_function
more... - peroxisome proliferator activated receptor binding
- phosphatidate phosphatase activity
- transcription coactivator activity
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|
| |
IFRD1 | 20 |
BP MF CC |
biological_process | - adult somatic muscle development
- multicellular organismal development
- muscle cell differentiation
- myoblast cell fate determination
more...
|
| | | |
CYP1B1 | 20 |
BP MF CC |
biological_process | - angiogenesis
- cellular aromatic compound metabolic process
- endothelial cell migration
- endothelial cell-cell adhesion
more... - estrogen metabolic process
- oxidation-reduction process
- response to organic substance
- response to toxin
- retina vasculature development in camera-type eye
- toxin metabolic process
- visual perception
- xenobiotic metabolic process
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|
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- membrane
- microsome
more...
|
| molecular_function | - aromatase activity
- electron carrier activity
- heme binding
- metal ion binding
more... - monooxygenase activity
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- oxygen binding
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|
| |
PCK2 | 20 |
BP MF CC |
| cellular_component | - mitochondrial matrix
- mitochondrion
- soluble fraction
|
| molecular_function | - GTP binding
- kinase activity
- lyase activity
- metal ion binding
more... - phosphoenolpyruvate carboxykinase (GTP) activity
- phosphoenolpyruvate carboxykinase activity
- purine nucleotide binding
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|
| |
PMAIP1 | 20 |
BP MF CC |
biological_process | - T cell homeostasis
- activation of caspase activity
- activation of pro-apoptotic gene products
- apoptosis
more... - cellular component disassembly involved in apoptosis
- cellular response to glucose starvation
- cellular response to hypoxia
- induction of apoptosis
- induction of apoptosis by intracellular signals
- negative regulation of fibroblast proliferation
- negative regulation of mitochondrial membrane potential
- positive regulation of DNA damage response, signal transduction by p53 class mediator
- positive regulation of apoptosis
- positive regulation of caspase activity
- positive regulation of glucose metabolic process
- positive regulation of neuron apoptosis
- positive regulation of protein oligomerization
- positive regulation of release of cytochrome c from mitochondria
- proteasomal protein catabolic process
- protein insertion into mitochondrial membrane involved in induction of apoptosis
- reactive oxygen species metabolic process
- regulation of mitochondrial membrane permeability
- response to DNA damage stimulus
- response to UV
- response to X-ray
- response to dsRNA
- signal transduction by p53 class mediator resulting in induction of apoptosis
- virus-infected cell apoptosis
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|
| cellular_component | - cytosol
- mitochondrial outer membrane
- mitochondrion
- nucleus
more...
|
| | |
SEPHS2 | 20 |
BP MF CC |
biological_process | - selenocysteine biosynthetic process
|
| | molecular_function | - ATP binding
- catalytic activity
- nucleotide binding
- selenide, water dikinase activity
more... - transferase activity
less...
|
| |
IFI27 | 20 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
- mitochondrial outer membrane
- mitochondrion
more...
|
| | |
GADD45A | 20 |
BP MF CC |
biological_process | - DNA repair
- G2/M transition of mitotic cell cycle
- apoptosis
- cell cycle arrest
more... - cellular response to ionizing radiation
- cellular response to mechanical stimulus
- centrosome cycle
- negative regulation of protein kinase activity
- positive regulation of reactive oxygen species metabolic process
- regulation of cyclin-dependent protein kinase activity
- signal transduction in response to DNA damage
less...
|
| | | |
KIF2A | 20 |
BP MF CC |
biological_process | - M phase of mitotic cell cycle
- blood coagulation
- cell differentiation
- cell division
more... - microtubule-based movement
- mitotic cell cycle
- mitotic prometaphase
- mitotic spindle organization
- multicellular organismal development
- nervous system development
less...
|
| | molecular_function | - ATP binding
- microtubule motor activity
- motor activity
- nucleotide binding
more... - protein binding
less...
|
| |
FOXO3 | 20 |
BP MF CC |
biological_process | - DNA damage response, signal transduction by p53 class mediator
- antral ovarian follicle growth
- apoptosis
- embryo development
more... - fibroblast growth factor receptor signaling pathway
- glucose homeostasis
- induction of apoptosis
- initiation of primordial ovarian follicle growth
- insulin receptor signaling pathway
- negative regulation of transcription from RNA polymerase II promoter
- nerve growth factor receptor signaling pathway
- oocyte maturation
- ovulation from ovarian follicle
- pattern specification process
- phosphatidylinositol-mediated signaling
- positive regulation of erythrocyte differentiation
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- regulation of cell proliferation
- regulation of sequence-specific DNA binding transcription factor activity
- response to DNA damage stimulus
- tissue development
- transcription, DNA-dependent
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|
| | molecular_function | - DNA bending activity
- double-stranded DNA binding
- protein binding
- protein kinase binding
more... - sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
- sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
- transcription factor binding
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|
| |
HMGCS1 | 20 |
BP MF CC |
biological_process | - brain development
- cellular response to cholesterol
- cellular response to follicle-stimulating hormone stimulus
- cellular response to organic cyclic compound
more... - cholesterol biosynthetic process
- isoprenoid biosynthetic process
- lipid metabolic process
- liver development
- male gonad development
- response to acid
- response to drug
- response to gonadotropin stimulus
- response to lipoprotein stimulus
- response to low light intensity stimulus
- response to organic nitrogen
- response to purine-containing compound
- response to tellurium ion
- response to vitamin E
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|
| cellular_component | - cytoplasm
- cytosol
- soluble fraction
|
| | |
IRS1 | 20 |
BP MF CC |
biological_process | - cellular response to insulin stimulus
- fibroblast growth factor receptor signaling pathway
- glucose homeostasis
- insulin receptor signaling pathway
more... - insulin-like growth factor receptor signaling pathway
- lipid catabolic process
- mammary gland development
- negative regulation of insulin receptor signaling pathway
- negative regulation of insulin secretion
- negative regulation of somatostatin secretion
- nerve growth factor receptor signaling pathway
- phosphatidylinositol 3-kinase cascade
- phosphatidylinositol-mediated signaling
- positive regulation of cell migration
- positive regulation of cell proliferation
- positive regulation of fatty acid beta-oxidation
- positive regulation of glucagon secretion
- positive regulation of glucose import
- positive regulation of glucose metabolic process
- positive regulation of glycogen biosynthetic process
- positive regulation of insulin receptor signaling pathway
- positive regulation of mesenchymal cell proliferation
- positive regulation of phosphatidylinositol 3-kinase activity
- positive regulation of phosphorylation
- protein heterooligomerization
- protein localization to nucleus
- regulation of gene expression
- response to insulin stimulus
- response to peptide hormone stimulus
- signal transduction
- transmembrane receptor protein tyrosine kinase signaling pathway
less...
|
| | molecular_function | - SH2 domain binding
- insulin receptor binding
- insulin-like growth factor receptor binding
- insulin-like growth factor-activated receptor activity
more... - phosphatidylinositol 3-kinase binding
- phosphatidylinositol-4,5-bisphosphate 3-kinase activity
- protein binding
- protein kinase C binding
- signal transducer activity
- transmembrane receptor protein tyrosine kinase adaptor activity
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|
| |
MAP2K4 | 18 |
BP MF CC |
biological_process | - JNK cascade
- MyD88-dependent toll-like receptor signaling pathway
- MyD88-independent toll-like receptor signaling pathway
- Toll signaling pathway
more... - cellular response to mechanical stimulus
- innate immune response
- protein phosphorylation
- signal transduction
- stress-activated MAPK cascade
- toll-like receptor 1 signaling pathway
- toll-like receptor 2 signaling pathway
- toll-like receptor 3 signaling pathway
- toll-like receptor 4 signaling pathway
- toll-like receptor signaling pathway
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|
| | | |
CEBPG | 18 |
BP MF CC |
biological_process | - B cell differentiation
- enucleate erythrocyte differentiation
- immune response
- liver development
more... - mRNA metabolic process
- natural killer cell mediated cytotoxicity
- negative regulation of sequence-specific DNA binding transcription factor activity
- positive regulation of DNA binding
- positive regulation of DNA repair
- positive regulation of interferon-gamma biosynthetic process
- positive regulation of sequence-specific DNA binding transcription factor activity
- regulation of transcription from RNA polymerase II promoter
less...
|
| | | |
N4BP2L2 | 18 |
BP MF CC |
|
SC4MOL | 18 |
BP MF CC |
biological_process | - cholesterol biosynthetic process
- fatty acid biosynthetic process
- fatty acid metabolic process
- steroid metabolic process
more...
|
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- plasma membrane
more...
|
| molecular_function | - C-4 methylsterol oxidase activity
- iron ion binding
- oxidoreductase activity
|
| |
CTAGE5 | 18 |
BP MF CC |
biological_process | - positive regulation of catalytic activity
|
| | molecular_function | - enzyme activator activity
|
| |
GOT1 | 18 |
BP MF CC |
biological_process | - 2-oxoglutarate metabolic process
- L-methionine salvage from methylthioadenosine
- aspartate catabolic process
- aspartate metabolic process
more... - biosynthetic process
- carbohydrate metabolic process
- cellular amino acid biosynthetic process
- cellular amino acid metabolic process
- cellular nitrogen compound metabolic process
- cellular response to insulin stimulus
- gluconeogenesis
- glucose metabolic process
- glutamate metabolic process
- polyamine metabolic process
- response to glucocorticoid stimulus
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|
| cellular_component | - axon terminus
- cytoplasm
- cytosol
- lysosome
more... - soluble fraction
less...
|
| molecular_function | - L-aspartate:2-oxoglutarate aminotransferase activity
- L-phenylalanine:2-oxoglutarate aminotransferase activity
- carboxylic acid binding
- pyridoxal phosphate binding
more... - transaminase activity
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|
| |
HSPA5 | 18 |
BP MF CC |
biological_process | - ATP catabolic process
- ER overload response
- ER-associated protein catabolic process
- activation of signaling protein activity involved in unfolded protein response
more... - anti-apoptosis
- blood coagulation
- cellular response to glucose starvation
- cerebellar Purkinje cell layer development
- cerebellum structural organization
- endoplasmic reticulum unfolded protein response
- negative regulation of apoptosis
- negative regulation of caspase activity
- negative regulation of transforming growth factor beta receptor signaling pathway
- platelet activation
- platelet degranulation
- positive regulation of protein ubiquitination
- proteolysis involved in cellular protein catabolic process
- regulation of protein folding in endoplasmic reticulum
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|
| cellular_component | - caspase complex
- cell surface
- endoplasmic reticulum
- endoplasmic reticulum chaperone complex
more... - endoplasmic reticulum lumen
- endoplasmic reticulum membrane
- endoplasmic reticulum-Golgi intermediate compartment
- extracellular region
- integral to endoplasmic reticulum membrane
- melanosome
- midbody
- nucleus
- perinuclear region of cytoplasm
- signalosome
less...
|
| molecular_function | - ATP binding
- ATPase activity
- calcium ion binding
- caspase inhibitor activity
more... - chaperone binding
- misfolded protein binding
- nucleotide binding
- protein binding
- protein binding, bridging
- protein domain specific binding
- ribosome binding
- ubiquitin protein ligase binding
- unfolded protein binding
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|
| |
CARS | 18 |
BP MF CC |
biological_process | - cysteinyl-tRNA aminoacylation
- gene expression
- tRNA aminoacylation for protein translation
|
| | | |
ATF2 | 18 |
BP MF CC |
biological_process | - MyD88-dependent toll-like receptor signaling pathway
- MyD88-independent toll-like receptor signaling pathway
- Toll signaling pathway
- adipose tissue development
more... - fat cell differentiation
- innate immune response
- outflow tract morphogenesis
- positive regulation of transforming growth factor beta2 production
- regulation of sequence-specific DNA binding transcription factor activity
- regulation of transcription, DNA-dependent
- stress-activated MAPK cascade
- toll-like receptor 1 signaling pathway
- toll-like receptor 2 signaling pathway
- toll-like receptor 3 signaling pathway
- toll-like receptor 4 signaling pathway
- toll-like receptor signaling pathway
- transcription, DNA-dependent
less...
|
| cellular_component | - intracellular
- membrane fraction
- nucleolus
- nucleoplasm
more... - nucleus
less...
|
| molecular_function | - DNA binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
- chromatin binding
- metal ion binding
more... - nucleic acid binding
- protein binding
- protein dimerization activity
- sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
- transcription coactivator activity
- zinc ion binding
less...
|
| |
NFE2L2 | 18 |
BP MF CC |
biological_process | - cellular response to oxidative stress
- endoplasmic reticulum unfolded protein response
- positive regulation of blood coagulation
- positive regulation of reactive oxygen species metabolic process
more... - positive regulation of transcription from RNA polymerase II promoter
- regulation of embryonic development
- regulation of removal of superoxide radicals
- regulation of transcription, DNA-dependent
- transcription from RNA polymerase II promoter
less...
|
| cellular_component | - centrosome
- chromatin
- cytoplasm
- cytosol
more... - nucleus
- plasma membrane
less...
|
| | |
RIT1 | 18 |
BP MF CC |
biological_process | - nerve growth factor receptor signaling pathway
- signal transduction
- small GTPase mediated signal transduction
|
| | molecular_function | - GTP binding
- GTPase activity
- calmodulin binding
- nucleotide binding
more... - protein binding
less...
|
| |
GARS | 18 |
BP MF CC |
|
AARS | 18 |
BP MF CC |
biological_process | - alanyl-tRNA aminoacylation
- cerebellar Purkinje cell layer development
- endoplasmic reticulum unfolded protein response
- gene expression
more... - hair follicle development
- negative regulation of neuron apoptosis
- neuromuscular process controlling balance
- protein folding
- response to amino acid stimulus
- skin development
- tRNA aminoacylation
- tRNA aminoacylation for protein translation
- tRNA modification
- tRNA processing
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|
| cellular_component | - cytoplasm
- cytosol
- soluble fraction
|
| molecular_function | - ATP binding
- alanine-tRNA ligase activity
- amino acid binding
- aminoacyl-tRNA editing activity
more... - ligase activity
- ligase activity, forming aminoacyl-tRNA and related compounds
- metal ion binding
- nucleic acid binding
- nucleotide binding
- tRNA binding
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|
| |
FUS | 18 |
BP MF CC |
biological_process | - RNA splicing
- cell death
- gene expression
- nuclear mRNA splicing, via spliceosome
more...
|
| cellular_component | - cytoplasm
- intracellular
- nucleolus
- nucleoplasm
more... - nucleus
less...
|
| | |
HBP1 | 18 |
BP MF CC |
biological_process | - Wnt receptor signaling pathway
- cell cycle arrest
- regulation of transcription, DNA-dependent
|
| | | |
BRCA1 | 16 |
BP MF CC |
biological_process | - DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
- DNA damage response, signal transduction resulting in induction of apoptosis
- DNA recombination
- DNA repair
more... - DNA replication
- G2/M transition DNA damage checkpoint
- androgen receptor signaling pathway
- apoptosis
- brain development
- cell cycle
- cellular response to indole-3-methanol
- centrosome cycle
- chordate embryonic development
- chromosome segregation
- dosage compensation, by inactivation of X chromosome
- double-strand break repair
- double-strand break repair via homologous recombination
- negative regulation of centriole replication
- negative regulation of fatty acid biosynthetic process
- negative regulation of histone H3-K9 methylation
- negative regulation of transcription, DNA-dependent
- positive regulation of DNA repair
- positive regulation of cell cycle arrest
- positive regulation of histone H3-K4 methylation
- positive regulation of histone H3-K9 acetylation
- positive regulation of histone H4-K16 acetylation
- positive regulation of histone H4-K20 methylation
- positive regulation of histone acetylation
- positive regulation of protein ubiquitination
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- postreplication repair
- protein K6-linked ubiquitination
- protein autoubiquitination
- protein ubiquitination
- regulation of apoptosis
- regulation of cell motility
- regulation of cell proliferation
- regulation of transcription from RNA polymerase II promoter
- regulation of transcription from RNA polymerase III promoter
- response to DNA damage stimulus
- response to estradiol stimulus
- response to estrogen stimulus
- response to ionizing radiation
- response to lipid
- response to nutrient
- substrate adhesion-dependent cell spreading
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|
| cellular_component | - BRCA1-A complex
- BRCA1-BARD1 complex
- condensed nuclear chromosome
- cytoplasm
more... - filamentous actin
- focal adhesion
- gamma-tubulin ring complex
- intracellular
- mitochondrial matrix
- nucleoplasm
- nucleus
- plasma membrane
- protein complex
- ribonucleoprotein complex
- ruffle
- ubiquitin ligase complex
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|
| molecular_function | - DNA binding
- RNA binding
- androgen receptor binding
- damaged DNA binding
more... - enzyme binding
- ligase activity
- metal ion binding
- protein binding
- transcription coactivator activity
- transcription regulatory region DNA binding
- tubulin binding
- ubiquitin protein ligase binding
- ubiquitin-protein ligase activity
- zinc ion binding
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|
| |
SMAD5 | 16 |
BP MF CC |
|
SLC20A1 | 16 |
BP MF CC |
| cellular_component | - integral to plasma membrane
- membrane
- plasma membrane
|
| | |
VEGFA | 16 |
BP MF CC |
biological_process | - T-helper 1 type immune response
- activation of protein kinase activity
- angiogenesis
- anti-apoptosis
more... - artery morphogenesis
- basophil chemotaxis
- behavior
- blood coagulation
- blood vessel remodeling
- camera-type eye morphogenesis
- cardiac muscle fiber development
- cell maturation
- cell migration involved in sprouting angiogenesis
- cellular response to hypoxia
- cellular response to vascular endothelial growth factor stimulus
- endothelial cell chemotaxis
- epithelial cell differentiation
- eye photoreceptor cell development
- growth
- heart morphogenesis
- in utero embryonic development
- induction of positive chemotaxis
- kidney development
- lactation
- lung alveolus development
- mRNA stabilization
- mammary gland alveolus development
- mesoderm development
- multicellular organismal development
- negative regulation of apoptosis
- negative regulation of bone resorption
- nervous system development
- ovarian follicle development
- patterning of blood vessels
- platelet activation
- platelet degranulation
- platelet-derived growth factor receptor signaling pathway
- positive chemotaxis
- positive regulation of CREB transcription factor activity
- positive regulation of MAP kinase activity
- positive regulation of angiogenesis
- positive regulation of blood vessel endothelial cell migration
- positive regulation of branching involved in ureteric bud morphogenesis
- positive regulation of cell adhesion
- positive regulation of cell division
- positive regulation of cell migration
- positive regulation of cell proliferation
- positive regulation of cellular component movement
- positive regulation of endothelial cell migration
- positive regulation of endothelial cell proliferation
- positive regulation of intracellular protein kinase cascade
- positive regulation of leukocyte migration
- positive regulation of mast cell chemotaxis
- positive regulation of mesenchymal cell proliferation
- positive regulation of peptidyl-serine phosphorylation
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of positive chemotaxis
- positive regulation of protein autophosphorylation
- positive regulation of protein kinase C signaling cascade
- positive regulation of smooth muscle cell proliferation
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of vascular endothelial growth factor receptor signaling pathway
- positive regulation of vascular permeability
- post-embryonic camera-type eye development
- primitive erythrocyte differentiation
- regulation of cell shape
- response to cold
- response to hypoxia
- surfactant homeostasis
- vascular endothelial growth factor receptor signaling pathway
- vasculogenesis
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|
| cellular_component | - basement membrane
- cell surface
- cytoplasm
- extracellular region
more... - extracellular space
- membrane
- membrane-bounded vesicle
- platelet alpha granule lumen
- proteinaceous extracellular matrix
- stored secretory granule
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|
| molecular_function | - cell surface binding
- chemoattractant activity
- cytokine activity
- extracellular matrix binding
more... - fibronectin binding
- growth factor activity
- heparin binding
- platelet-derived growth factor receptor binding
- protein binding
- protein heterodimerization activity
- protein homodimerization activity
- vascular endothelial growth factor receptor 1 binding
- vascular endothelial growth factor receptor 2 binding
- vascular endothelial growth factor receptor binding
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|
| |
CDC6 | 16 |
BP MF CC |
biological_process | - DNA replication
- DNA replication checkpoint
- G1/S transition of mitotic cell cycle
- M/G1 transition of mitotic cell cycle
more... - S phase of mitotic cell cycle
- cell cycle checkpoint
- cell division
- mitosis
- mitotic cell cycle
- negative regulation of DNA replication
- negative regulation of cell proliferation
- positive regulation of cell cycle cytokinesis
- positive regulation of chromosome segregation
- regulation of cyclin-dependent protein kinase activity
- regulation of mitotic anaphase
- regulation of transcription involved in G1/S phase of mitotic cell cycle
- traversing start control point of mitotic cell cycle
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|
| | | |
TARS | 14 |
BP MF CC |
biological_process | - gene expression
- tRNA aminoacylation for protein translation
- threonyl-tRNA aminoacylation
- translation
more...
|
| | | |
PRIM1 | 14 |
BP MF CC |
biological_process | - DNA replication
- DNA replication, synthesis of RNA primer
- DNA strand elongation involved in DNA replication
- DNA-dependent DNA replication initiation
more... - G1/S transition of mitotic cell cycle
- M/G1 transition of mitotic cell cycle
- S phase of mitotic cell cycle
- mitotic cell cycle
- telomere maintenance
- telomere maintenance via recombination
- telomere maintenance via semi-conservative replication
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|
| cellular_component | - alpha DNA polymerase:primase complex
- nucleoplasm
|
| molecular_function | - DNA primase activity
- metal ion binding
- nucleotidyltransferase activity
- transferase activity
more...
|
| |
MCM7 | 14 |
BP MF CC |
biological_process | - DNA replication
- DNA strand elongation involved in DNA replication
- DNA unwinding involved in replication
- DNA-dependent DNA replication initiation
more... - G1/S transition of mitotic cell cycle
- M/G1 transition of mitotic cell cycle
- S phase of mitotic cell cycle
- cell cycle checkpoint
- cell proliferation
- mitotic cell cycle
- regulation of phosphorylation
- response to DNA damage stimulus
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|
| cellular_component | - MCM complex
- chromatin
- nucleoplasm
- nucleus
more...
|
| molecular_function | - ATP binding
- ATP-dependent DNA helicase activity
- DNA binding
- DNA helicase activity
more... - hydrolase activity
- nucleoside-triphosphatase activity
- nucleotide binding
- protein binding
- single-stranded DNA binding
less...
|
| |
CDKN1A | 14 |
BP MF CC |
biological_process | - DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
- G1 phase of mitotic cell cycle
- G1/S transition of mitotic cell cycle
- G2/M transition of mitotic cell cycle
more... - Ras protein signal transduction
- S phase of mitotic cell cycle
- cell cycle
- cell cycle arrest
- cell cycle checkpoint
- cellular response to extracellular stimulus
- cellular response to ionizing radiation
- cellular senescence
- induction of apoptosis by intracellular signals
- mitotic cell cycle
- negative regulation of apoptosis
- negative regulation of cell growth
- negative regulation of cell proliferation
- negative regulation of cyclin-dependent protein kinase activity
- negative regulation of gene expression
- negative regulation of phosphorylation
- organ regeneration
- phosphorylation
- positive regulation of B cell proliferation
- positive regulation of anti-apoptosis
- positive regulation of fibroblast proliferation
- positive regulation of programmed cell death
- positive regulation of reactive oxygen species metabolic process
- regulation of DNA biosynthetic process
- regulation of cyclin-dependent protein kinase activity
- regulation of mitotic cell cycle
- regulation of protein import into nucleus, translocation
- response to DNA damage stimulus
- response to UV
- response to arsenic-containing substance
- response to corticosterone stimulus
- response to drug
- response to hyperoxia
- response to organic cyclic compound
- response to organic nitrogen
- response to toxin
- stress-induced premature senescence
less...
|
| cellular_component | - PCNA-p21 complex
- cyclin-dependent protein kinase holoenzyme complex
- cytoplasm
- cytosol
more... - nucleoplasm
- nucleus
less...
|
| | |
NOTCH1 | 14 |
BP MF CC |
biological_process | - Notch receptor processing
- Notch signaling pathway
- anagen
- aortic valve morphogenesis
more... - axonogenesis
- branching morphogenesis of a tube
- cell differentiation in spinal cord
- cell fate specification
- compartment pattern specification
- determination of left/right symmetry
- embryo development
- embryonic hindlimb morphogenesis
- endoderm development
- forebrain development
- foregut morphogenesis
- gene expression
- hair follicle morphogenesis
- heart development
- immune response
- in utero embryonic development
- liver development
- lung development
- negative regulation of BMP signaling pathway
- negative regulation of apoptosis
- negative regulation of calcium ion-dependent exocytosis
- negative regulation of cell death
- negative regulation of cell-substrate adhesion
- negative regulation of glial cell proliferation
- negative regulation of myoblast differentiation
- negative regulation of oligodendrocyte differentiation
- negative regulation of osteoblast differentiation
- negative regulation of photoreceptor cell differentiation
- negative regulation of pro-B cell differentiation
- negative regulation of stem cell differentiation
- negative regulation of transcription from RNA polymerase II promoter
- negative regulation of transcription, DNA-dependent
- neural tube development
- neuron fate commitment
- neuronal stem cell maintenance
- organ regeneration
- positive regulation of BMP signaling pathway
- positive regulation of JAK-STAT cascade
- positive regulation of apoptosis
- positive regulation of astrocyte differentiation
- positive regulation of cell proliferation
- positive regulation of endothelial cell differentiation
- positive regulation of epithelial cell proliferation
- positive regulation of epithelial to mesenchymal transition
- positive regulation of keratinocyte differentiation
- positive regulation of neuroblast proliferation
- positive regulation of transcription of Notch receptor target
- positive regulation of transcription, DNA-dependent
- prostate gland epithelium morphogenesis
- regulation of cardioblast proliferation
- regulation of developmental process
- regulation of epithelial cell proliferation involved in prostate gland development
- regulation of neurogenesis
- regulation of somitogenesis
- regulation of transcription, DNA-dependent
- response to corticosteroid stimulus
- response to lipopolysaccharide
- secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
- somatic stem cell division
- spermatogenesis
- sprouting angiogenesis
- tissue regeneration
less...
|
| cellular_component | - Golgi apparatus
- Golgi lumen
- MAML1-RBP-Jkappa- ICN1 complex
- acrosomal vesicle
more... - cytoplasm
- cytosol
- endoplasmic reticulum lumen
- extracellular region
- integral to membrane
- nucleoplasm
- nucleus
- plasma membrane
less...
|
| molecular_function | - calcium ion binding
- chromatin DNA binding
- core promoter binding
- protein binding
more... - receptor activity
- sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
less...
|
| |
LAMC2 | 14 |
BP MF CC |
biological_process | - cell adhesion
- cell junction assembly
- epidermis development
- hemidesmosome assembly
more...
|
| cellular_component | - basement membrane
- cell cortex
- extracellular matrix
- extracellular region
more... - extracellular space
- laminin-2 complex
- membrane fraction
- perinuclear region of cytoplasm
- soluble fraction
less...
|
| | |
EGFR | 14 |
BP MF CC |
biological_process | - activation of phospholipase A2 activity by calcium-mediated signaling
- activation of phospholipase C activity
- axon guidance
- cell morphogenesis
more... - cell proliferation
- cell surface receptor linked signaling pathway
- cell-cell adhesion
- cerebral cortex cell migration
- digestive tract morphogenesis
- embryonic placenta development
- epidermal growth factor receptor signaling pathway
- hair follicle development
- morphogenesis of an epithelial fold
- negative regulation of apoptosis
- negative regulation of epidermal growth factor receptor signaling pathway
- ossification
- positive regulation of MAP kinase activity
- positive regulation of catenin import into nucleus
- positive regulation of cell migration
- positive regulation of cell proliferation
- positive regulation of cyclin-dependent protein kinase activity involved in G1/S
- positive regulation of epithelial cell proliferation
- positive regulation of fibroblast proliferation
- positive regulation of nitric oxide biosynthetic process
- positive regulation of phosphorylation
- positive regulation of protein kinase B signaling cascade
- protein autophosphorylation
- protein insertion into membrane
- protein phosphorylation
- regulation of nitric-oxide synthase activity
- regulation of peptidyl-tyrosine phosphorylation
- response to UV-A
- response to stress
- salivary gland morphogenesis
- signal transduction
- transmembrane receptor protein tyrosine kinase signaling pathway
less...
|
| cellular_component | - AP-2 adaptor complex
- Golgi apparatus
- Golgi membrane
- Shc-EGFR complex
more... - basolateral plasma membrane
- cytoplasm
- endocytic vesicle
- endoplasmic reticulum
- endoplasmic reticulum membrane
- endosome
- extracellular region
- extracellular space
- integral to membrane
- intracellular
- membrane
- membrane raft
- nuclear membrane
- nucleus
- perinuclear region of cytoplasm
- plasma membrane
less...
|
| molecular_function | - ATP binding
- MAP/ERK kinase kinase activity
- actin filament binding
- double-stranded DNA binding
more... - enzyme binding
- epidermal growth factor-activated receptor activity
- identical protein binding
- kinase activity
- nitric-oxide synthase regulator activity
- nucleotide binding
- protein binding
- protein heterodimerization activity
- protein phosphatase binding
- protein tyrosine kinase activity
- receptor activity
- receptor signaling protein tyrosine kinase activity
- signal transducer activity
- transmembrane receptor protein tyrosine kinase activity
- transmembrane signaling receptor activity
less...
|
| |
CREBBP | 12 |
BP MF CC |
biological_process | - N-terminal peptidyl-lysine acetylation
- cell proliferation
- cellular lipid metabolic process
- gene expression
more... - histone acetylation
- homeostatic process
- innate immune response
- interspecies interaction between organisms
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- protein complex assembly
- regulation of S phase
- regulation of transcription, DNA-dependent
- response to hypoxia
- signal transduction
- transcription, DNA-dependent
less...
|
| cellular_component | - cytoplasm
- histone acetyltransferase complex
- nuclear body
- nucleoplasm
more... - nucleus
less...
|
| molecular_function | - MyoD binding
- SMAD binding
- acetyltransferase activity
- histone acetyltransferase activity
more... - metal ion binding
- p53 binding
- peroxisome proliferator activated receptor binding
- protein binding
- sequence-specific DNA binding transcription factor activity
- signal transducer activity
- transcription coactivator activity
- transcription factor binding
- transferase activity
- zinc ion binding
less...
|
| |
GBP2 | 12 |
BP MF CC |
biological_process | - cytokine-mediated signaling pathway
- immune response
- interferon-gamma-mediated signaling pathway
- type I interferon-mediated signaling pathway
more...
|
| | molecular_function | - GTP binding
- GTPase activity
- nucleotide binding
|
| |
TFAP2C | 12 |
BP MF CC |
biological_process | - cell-cell signaling
- cerebral cortex development
- dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
- epithelial cell proliferation involved in mammary gland duct elongation
more... - forebrain neuron fate commitment
- germ-line stem cell maintenance
- hair follicle development
- keratinocyte development
- male gonad development
- negative regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription from RNA polymerase II promoter
- regulation of epidermis development
- regulation of transcription from RNA polymerase II promoter
- sebaceous gland development
- skin development
- somatic stem cell maintenance
- transcription, DNA-dependent
- trophectodermal cell differentiation
less...
|
| | molecular_function | - DNA binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
- RNA polymerase II distal enhancer sequence-specific DNA binding
more... - protein binding
- protein dimerization activity
- sequence-specific DNA binding RNA polymerase II transcription factor activity
- sequence-specific DNA binding transcription factor activity
less...
|
| |
ANGEL2 | 12 |
BP MF CC |
|
PPA1 | 12 |
BP MF CC |
biological_process | - diphosphate metabolic process
- gene expression
- phosphate-containing compound metabolic process
- tRNA aminoacylation for protein translation
more...
|
| | molecular_function | - hydrolase activity
- inorganic diphosphatase activity
- magnesium ion binding
|
| |
CLN5 | 12 |
BP MF CC |
|
N4BP1 | 12 |
BP MF CC |
biological_process | - negative regulation of proteasomal ubiquitin-dependent protein catabolic process
- negative regulation of protein ubiquitination
|
| | | |
PPAP2A | 12 |
BP MF CC |
biological_process | - activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
- androgen receptor signaling pathway
- germ cell migration
- lipid metabolic process
more... - negative regulation of cell proliferation
- phospholipid dephosphorylation
- regulation of lipid metabolic process
- sphingolipid metabolic process
- steroid hormone receptor signaling pathway
less...
|
| cellular_component | - integral to plasma membrane
- membrane fraction
- plasma membrane
|
| molecular_function | - hydrolase activity
- phosphatidate phosphatase activity
|
| |
GPD1L | 12 |
BP MF CC |
biological_process | - carbohydrate metabolic process
- glycerol-3-phosphate catabolic process
- oxidation-reduction process
|
| cellular_component | - cytoplasm
- glycerol-3-phosphate dehydrogenase complex
|
| molecular_function | - NAD binding
- binding
- glycerol-3-phosphate dehydrogenase [NAD+] activity
- protein homodimerization activity
more...
|
| |
NDUFA9 | 12 |
BP MF CC |
| | molecular_function | - 3-beta-hydroxy-delta5-steroid dehydrogenase activity
- NADH dehydrogenase (ubiquinone) activity
- NADH dehydrogenase activity
- binding
more... - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
less...
|
| |
IDH3A | 12 |
BP MF CC |
biological_process | - 2-oxoglutarate metabolic process
- NADH metabolic process
- carbohydrate metabolic process
- isocitrate metabolic process
more... - tricarboxylic acid cycle
less...
|
| cellular_component | - mitochondrial matrix
- mitochondrion
|
| molecular_function | - NAD binding
- isocitrate dehydrogenase (NAD+) activity
- magnesium ion binding
- oxidoreductase activity
more... - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
less...
|
| |
TMEM147 | 12 |
BP MF CC |
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- membrane
more...
|
| | |
KATNB1 | 12 |
BP MF CC |
biological_process | - cell cycle
- cell division
- microtubule severing
- mitosis
more... - negative regulation of microtubule depolymerization
- positive regulation of cell death
- positive regulation of microtubule depolymerization
- positive regulation of neuron projection development
- protein targeting
less...
|
| | molecular_function | - dynein binding
- microtubule binding
- microtubule-severing ATPase activity
- protein heterodimerization activity
more...
|
| |
ATP5B | 12 |
BP MF CC |
biological_process | - ADP biosynthetic process
- ATP biosynthetic process
- ATP catabolic process
- ATP hydrolysis coupled proton transport
more... - ATP metabolic process
- ATP synthesis coupled proton transport
- angiogenesis
- generation of precursor metabolites and energy
- ion transport
- lipid metabolic process
- mitochondrial ATP synthesis coupled proton transport
- negative regulation of cell adhesion involved in substrate-bound cell migration
- proton transport
- receptor-mediated endocytosis
- regulation of intracellular pH
- respiratory electron transport chain
- transport
less...
|
| cellular_component | - cell surface
- mitochondrial matrix
- mitochondrial membrane
- mitochondrial nucleoid
more... - mitochondrial proton-transporting ATP synthase complex
- mitochondrial proton-transporting ATP synthase, catalytic core
- mitochondrion
- plasma membrane
- proton-transporting ATP synthase complex, catalytic core F(1)
- proton-transporting two-sector ATPase complex
less...
|
| molecular_function | - ATP binding
- ATPase activity
- MHC class I protein binding
- calcium ion binding
more... - eukaryotic cell surface binding
- hydrogen ion transporting ATP synthase activity, rotational mechanism
- hydrogen-exporting ATPase activity, phosphorylative mechanism
- hydrolase activity
- hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- lipoprotein particle receptor activity
- nucleoside-triphosphatase activity
- nucleotide binding
- protein binding
- proton-transporting ATPase activity, rotational mechanism
- transmembrane transporter activity
- transporter activity
less...
|
| |
RMND5B | 12 |
BP MF CC |
|
DDX24 | 12 |
BP MF CC |
|
PLEKHM1 | 12 |
BP MF CC |
biological_process | - intracellular signal transduction
|
| | | |
MTMR1 | 12 |
BP MF CC |
| cellular_component | - cellular_component
- plasma membrane
|
| molecular_function | - hydrolase activity
- phosphatase activity
- protein tyrosine phosphatase activity
|
| |
NDRG2 | 12 |
BP MF CC |
biological_process | - cell differentiation
- multicellular organismal development
- negative regulation of ERK1 and ERK2 cascade
- negative regulation of cytokine production
more... - negative regulation of smooth muscle cell proliferation
- nervous system development
- regulation of platelet-derived growth factor production
- regulation of vascular endothelial growth factor production
- signal transduction
less...
|
| | molecular_function | - molecular_function
- protein binding
|
| |
COPS4 | 12 |
BP MF CC |
| cellular_component | - cytoplasm
- nucleus
- signalosome
|
| | |
EIF5 | 12 |
BP MF CC |
|
TBC1D15 | 12 |
BP MF CC |
biological_process | - positive regulation of Rab GTPase activity
- regulation of Rab GTPase activity
|
| cellular_component | - cytoplasm
- extracellular region
- intracellular
- mitochondrion
more...
|
| molecular_function | - GTPase activator activity
- Rab GTPase activator activity
- protein binding
|
| |
WDR45 | 12 |
BP MF CC |
biological_process | - autophagy
- response to starvation
|
| | molecular_function | - phosphatidylinositol-3,5-bisphosphate binding
- small GTPase regulator activity
|
| |
ATF4 | 12 |
BP MF CC |
biological_process | - cellular amino acid metabolic process
- gluconeogenesis
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
more... - regulation of transcription, DNA-dependent
- response to endoplasmic reticulum stress
- transcription from RNA polymerase II promoter
- transcription, DNA-dependent
less...
|
| | | |
TSN | 12 |
BP MF CC |
| | molecular_function | - DNA binding
- mRNA binding
- sequence-specific DNA binding
|
| |
AKR1A1 | 12 |
BP MF CC |
| cellular_component | - apical plasma membrane
- cytosol
|
| molecular_function | - L-glucuronate reductase activity
- alditol:NADP+ 1-oxidoreductase activity
- electron carrier activity
- oxidoreductase activity
more...
|
| |
ADAM9 | 12 |
BP MF CC |
biological_process | - PMA-inducible membrane protein ectodomain proteolysis
- activation of MAPKK activity
- cell adhesion
- cell adhesion mediated by integrin
more... - cell-cell adhesion mediated by integrin
- cell-matrix adhesion
- integrin-mediated signaling pathway
- keratinocyte differentiation
- membrane protein ectodomain proteolysis
- monocyte activation
- positive regulation of cell adhesion mediated by integrin
- positive regulation of keratinocyte migration
- positive regulation of macrophage fusion
- positive regulation of membrane protein ectodomain proteolysis
- positive regulation of protein secretion
- proteolysis
- response to calcium ion
- response to glucocorticoid stimulus
- response to hydrogen peroxide
- response to manganese ion
- response to tumor necrosis factor
- transforming growth factor beta receptor signaling pathway
less...
|
| | molecular_function | - SH3 domain binding
- collagen binding
- integrin binding
- laminin binding
more... - metal ion binding
- metalloendopeptidase activity
- metallopeptidase activity
- peptidase activity
- protein binding
- protein kinase C binding
- zinc ion binding
less...
|
| |
NCKAP1 | 12 |
BP MF CC |
biological_process | - apoptosis
- central nervous system development
|
| cellular_component | - cell projection
- integral to membrane
- lamellipodium membrane
- plasma membrane
more...
|
| | |
SERPING1 | 12 |
BP MF CC |
biological_process | - blood circulation
- blood coagulation
- blood coagulation, intrinsic pathway
- complement activation, classical pathway
more... - innate immune response
- negative regulation of complement activation, lectin pathway
- negative regulation of endopeptidase activity
- platelet activation
- platelet degranulation
less...
|
| cellular_component | - extracellular region
- extracellular space
- platelet alpha granule lumen
|
| molecular_function | - peptidase activity
- peptidase inhibitor activity
- protein binding
- serine-type endopeptidase inhibitor activity
more...
|
| |
ANKRD46 | 12 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
|
| | |
LPAR6 | 12 |
BP MF CC |
biological_process | - G-protein coupled receptor protein signaling pathway
|
| cellular_component | - integral to membrane
- plasma membrane
|
| molecular_function | - G-protein coupled receptor activity
- purinergic nucleotide receptor activity, G-protein coupled
- receptor activity
- signal transducer activity
more...
|
| |
GLT8D1 | 12 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
- mitochondrion
|
| molecular_function | - transferase activity, transferring glycosyl groups
|
| |
RPS17 | 12 |
BP MF CC |
biological_process | - RNA metabolic process
- cellular protein metabolic process
- endocrine pancreas development
- erythrocyte homeostasis
more... - gene expression
- mRNA metabolic process
- rRNA processing
- ribosomal small subunit assembly
- ribosomal small subunit biogenesis
- translation
- translational elongation
- translational initiation
- translational termination
- viral infectious cycle
- viral reproduction
- viral transcription
less...
|
| cellular_component | - cytosol
- cytosolic small ribosomal subunit
- intracellular
- ribosome
more...
|
| molecular_function | - structural constituent of ribosome
|
| |
SLC25A20 | 12 |
BP MF CC |
biological_process | - carnitine shuttle
- cellular lipid metabolic process
- regulation of fatty acid oxidation
- transport
more...
|
| cellular_component | - integral to membrane
- membrane
- mitochondrial inner membrane
- mitochondrion
more...
|
| | |
DUSP1 | 12 |
BP MF CC |
biological_process | - cell cycle
- cellular response to hormone stimulus
- endoderm formation
- inactivation of MAPK activity
more... - intracellular signal transduction
- positive regulation of anti-apoptosis
- positive regulation of apoptosis
- protein dephosphorylation
- regulation of apoptosis
- response to cAMP
- response to calcium ion
- response to estradiol stimulus
- response to glucocorticoid stimulus
- response to hydrogen peroxide
- response to light stimulus
- response to oxidative stress
- response to retinoic acid
- response to testosterone stimulus
less...
|
| cellular_component | - nucleoplasm
- nucleus
- soluble fraction
|
| | |
SKP2 | 12 |
BP MF CC |
biological_process | - G1/S transition of mitotic cell cycle
- G2/M transition of mitotic cell cycle
- S phase of mitotic cell cycle
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
more... - cell proliferation
- mitotic cell cycle
- negative regulation of survival gene product expression
- positive regulation of estrogen receptor signaling pathway
- protein polyubiquitination
- regulation of cell cycle
- ubiquitin-dependent protein catabolic process
less...
|
| cellular_component | - SCF ubiquitin ligase complex
- cytosol
- nucleoplasm
|
| molecular_function | - kinase activity
- protein binding
- ubiquitin-protein ligase activity
|
| |
COL7A1 | 12 |
BP MF CC |
biological_process | - cell adhesion
- epidermis development
|
| cellular_component | - basement membrane
- collagen
- collagen type VII
- extracellular region
more...
|
| molecular_function | - peptidase inhibitor activity
- protein binding
- serine-type endopeptidase inhibitor activity
|
| |
SUCLG2 | 12 |
BP MF CC |
biological_process | - succinyl-CoA metabolic process
- tricarboxylic acid cycle
|
| cellular_component | - mitochondrial matrix
- mitochondrion
|
| | |
TMEM40 | 12 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
|
| | |
ARL6IP5 | 12 |
BP MF CC |
biological_process | - L-glutamate transport
- negative regulation of transport
|
| cellular_component | - cytoplasm
- endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
more... - membrane
less...
|
| molecular_function | - protein C-terminus binding
|
| |
ZMAT3 | 12 |
BP MF CC |
| cellular_component | - intracellular
- nucleolus
- nucleus
|
| molecular_function | - RNA binding
- metal ion binding
- nucleic acid binding
- zinc ion binding
more...
|
| |
C1orf50 | 12 |
BP MF CC |
|
GPR161 | 12 |
BP MF CC |
biological_process | - G-protein coupled receptor protein signaling pathway
- multicellular organismal development
|
| cellular_component | - integral to membrane
- plasma membrane
|
| molecular_function | - G-protein coupled receptor activity
- receptor activity
- signal transducer activity
|
| |
TRAK2 | 12 |
BP MF CC |
biological_process | - protein O-linked glycosylation
- protein targeting
- regulation of transcription from RNA polymerase II promoter
- transport
more...
|
| cellular_component | - cytoplasm
- early endosome
- nucleus
- plasma membrane
more...
|
| molecular_function | - GABA receptor binding
- enzyme binding
- protein binding
- receptor binding
more...
|
| |
TM2D1 | 12 |
BP MF CC |
biological_process | - apoptosis
- induction of apoptosis by extracellular signals
|
| cellular_component | - integral to plasma membrane
- membrane
|
| molecular_function | - G-protein coupled receptor activity
- beta-amyloid binding
|
| |
CASP8 | 12 |
BP MF CC |
biological_process | - activation of caspase activity
- activation of innate immune response
- activation of pro-apoptotic gene products
- angiogenesis
more... - apoptosis
- cellular component disassembly involved in apoptosis
- cellular response to mechanical stimulus
- heart development
- induction of apoptosis by extracellular signals
- induction of apoptosis by intracellular signals
- innate immune response
- macrophage differentiation
- neural tube formation
- nucleotide-binding oligomerization domain containing signaling pathway
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- protein heterooligomerization
- proteolysis
- proteolysis involved in cellular protein catabolic process
- regulation of apoptosis
- response to antibiotic
- response to cobalt ion
- response to cold
- response to estradiol stimulus
- response to ethanol
- response to lipopolysaccharide
- response to tumor necrosis factor
less...
|
| cellular_component | - CD95 death-inducing signaling complex
- Noc1p-Noc2p complex
- cell body
- centrosome
more... - cytoplasm
- cytoskeleton
- cytosol
- death-inducing signaling complex
- membrane raft
- mitochondrial outer membrane
- mitochondrion
- neuron projection
- nucleolus
- nucleus
- protein complex
less...
|
| | |